Local tissue reaction after implantation of biomaterials into the human body
. Cause the calcification of the material itself, but also the reasons for the body, such as the surface properties of the material, the death of cell deposition, local malnutrition,
the formation of calcification on the surface of biological materials often lead to loss of material function.
Local persistent infection, due to poor delivery of fiber capsule, lack of adequate immune cells, necrotic cells cleared slowly, so that infection persist or aggravate.
