When working with aluminum profiles, it's important to take several safety measures. Always wear appropriate personal protective equipment (PPE), including safety glasses to protect your eyes from flying debris, gloves to protect your hands, and a dust mask to prevent inhalation of dust particles. Ensure that the work area is well-ventilated to avoid inhaling aluminum dust. Use proper tools for cutting and shaping aluminum profiles to minimize the risk of injury. Keep the work area clean and free from clutter to prevent tripping hazards. Be cautious when handling sharp edges and ends of cut aluminum profiles. Lastly, be aware of the weight of the aluminum profiles to avoid back injuries when lifting.