Yes, a single-rope lifting system can be used in a building hoist. This system is common in construction elevators, where a single rope is used to lift and lower the hoist's cage. The rope is attached to a motor at the top and passes over sheaves or pulleys to provide mechanical advantage. It is essential to ensure that the rope is strong enough to support the load and that the system is equipped with safety features such as overload protection and emergency braking mechanisms to prevent accidents.