Aluminum profiles can affect the fire resistance of a building in several ways. While aluminum itself has a high melting point and doesn't burn, it does conduct heat, which can lead to rapid temperature increases in the structure. To mitigate this, aluminum profiles used in construction are often coated with fire-resistant materials or combined with non-combustible materials. Additionally, the design of the building and the use of fire barriers can help to slow the spread of fire and heat. It's crucial to follow building codes and standards that specify the appropriate use of aluminum in fire-resistant construction to ensure the safety and integrity of the structure during a fire.