How does aluminum affect the production of neurotransmitters?

Aluminum has been suggested to affect the production of neurotransmitters by potentially disrupting the normal functioning of enzymes and receptors involved in neurotransmitter synthesis and release. It may interfere with the uptake of essential metals like magnesium and zinc, which are crucial for the proper functioning of neurotransmitter systems. Aluminum can also alter the permeability of cell membranes, affecting the transport of neurotransmitters across the synaptic cleft. Additionally, there is evidence that aluminum may contribute to oxidative stress, which can impair the synthesis and function of neurotransmitters. However, it's important to note that the exact mechanisms are not fully understood, and more research is needed to establish a definitive link between aluminum exposure and neurotransmitter dysfunction.