Anesthesia machine manual and control APL valve should be in what state
so as to put the ball up for artificial ventilation. If you do not open the APL at this time, squeeze the balloon gas will run without any resistance and will not be squeezed into the lungs.
But in the manual mode if the patient has spontaneous breathing need to open the APL to the smallest, so that the equivalent of anesthesia machine as an oxygen source; and when the muscle loose drug onset, the patient does not have spontaneous breathing should be APL valve Open (usually we are playing in 30 or so), so as to put the ball up for artificial ventilation. If you do not open the APL at this time, squeeze the balloon gas will run without any resistance and will not be squeezed into the lungs.
Machine control state APL valve in what state is not a problem, as long as the machine switch can be opened.