Ceramic fibers themselves are not harmful to the ozone layer. They are inorganic, non-metallic materials that do not contain chlorine or bromine, which are the primary culprits in ozone depletion. However, it's important to note that the refrigerants used in some air conditioning systems can be harmful to the ozone layer if they contain substances like chlorofluorocarbons (CFCs) or hydrochlorofluorocarbons (HCFCs). Modern air conditioning systems are designed to use environmentally friendly refrigerants that do not deplete the ozone layer.