Yes, aluminum profiles can be used for exterior cladding systems that require fire resistance. Aluminum is a non-combustible material, which means it does not support combustion. However, it's important to note that while aluminum itself doesn't burn, it can melt at high temperatures. To enhance fire resistance, aluminum profiles can be coated with intumescent paint or used with fire-resistant materials in the cladding system. These measures can help to slow the spread of fire and protect the structure. Always ensure compliance with local building codes and fire safety regulations when selecting materials for fire-resistant applications.