I'm confused about one of the final scenes, where Seneca Crane is locked in the room with the nightlock berries. Does this mean that he is supposed to eat the berries and presumably die? Or is it symbolism of some sort of distaste in the way he ended the Games?
I think he is supposed to eat and die because Prez Snow got pretty angry at Seneca for having two winners for the Hunger Games
Yeah, basically President Snow has him killed. The berries represent this. The whole point is he goes into the room, sees the berries and knows he is being killed for allowing Katniss and Peeta to use those berries to cheat the system.
Yes, although it is only a movie adaptation; it isn't supposed to be mentioned in the first book. In Catching Fire, the second book of the trilogy, President Snow hints to Katniss that he had Seneca Crane executed because of his decision to let allow both Katniss and Peeta to emerge as victors, but his exact method of doing so was never mentioned; in the movie, it just reinforces this and heavily implies that the method of Seneca's execution is to lock him in a room with absolutely nothing but the nightlock berries, forcing him to commit suicide or eventually starve to death.