Floor is in camper trailer
I assume we are talking about a travel trailer. Some more description of the vehicle & the problem would be helpful. Although the problem can be caused by loose screws or bolts where the floor is secured to the chassis, it is almost always caused by a plywood floorboard that is loose from a crossmember within the floor itself. Often the problem will occur where two sections of flooring meet at a seam, where the loose one will rub against the edge of the one next to it. Many times the situation is as a result of water intrusion, damaging the wood or the fasteners. The correction is to resecure the loose board back down to the crossmember. It can be screwed or glued into place. This is easy enough, except that the carpet or vinyl flooring may need to be lifted to access the area, and if the wood is water-damaged additional work might be needed. An experienced RV technician can evaluate the problem pretty accurately just by walking on the area. You might run it by a reputable shop and ask for an inspection, and a free estimate.
Squeaks come from something rubbing. Rubbing comes from something moving against something moving less or stationary. Movement can be caused by a lot of things. Does it squeak when you walk on it? Walking puts weight on the floor. Weight can depress the floor, causing movement, causing rubbing, causing squeaking. (I am being very linear right now.) What kind of floor? Wood over a steel frame? Steel on steel? Welded or bolted? To stop the squeaking you can stop the movement by reinforcing the frame and floor so it doesn't flex when you walk on it. Extra cross pieces under the floor may stiffen the floor. Does the frame flex when the trailer is just supported by the axle and trailer tongue? What if you added more support at each corner of the trailer when the trailer is parked? Or you can stop the rubbing by attaching the rubbing parts so they don't move in relation to each other by tightening existing screws or bolts, or by installing additional screws or bolts between the floor and frame. Or you can try to eliminate the rubbing by separating the rubbing parts: neoprene or teflon washers or strips between floor and frame where they touch. You need to look under the trailer when someone is walking inside to see if you can locate the squeak and then observe what is the easiest repair. Thin wood wedges between frame and floor may be a temporary fix. Squeaks can be hard to fix, especially on vehicles that are not entirely rigid. Happy Trails.