Article 84 in GMP, the production equipment shall be cleaned according to the operating procedures specified in detail. Production equipment cleaning procedures shall stipulate detailed and complete cleaning methods, cleaning with the name of the equipment or tools, cleaning agents and preparation method, to remove the previous batch identification methods, protect already clean equipment before use from pollution methods, already clean equipment for the longest time limit, preserved...
Last year took part in the issue of dedicated to verify training on cleaning validation Wang Yanzhong teacher to explain this one is so blue font: if you don't clean immediately after the equipment use, such as when a couple of days to clean again, need to confirm according to have validated cleaning method can clean the equipment when cleaning equipment, there may be some material put a few days after has been hard on the equipment surface, not as easy as immediately when cleaning clean. So the time that the device is used up to cleaning is going to be validated.
It's ok for me to do it myself, and I can clean it for one week. Stay clean during the need after the sweep on the wash room, according to the requirement to avoid cross-contamination if contaminated with other material, and not be removed, the cleaning procedure if need to change the other material pollution, fashioning conservation measures
This time is dirty time, oneself according to the production requirements for 3 days, 3 days after completing equipment use clean, if qualified, cleaning validation then SOP can regulation equipment should be used in within 3 days from the end of the cleaning.
