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Question:

What are scaffolds in Tissue Engineering (TE)?

Please give me an explanation about scaffolds and what they are. Everything given is very appreciated. Thank you very much.

Answer:

What Are Scaffolds
Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physio-chemical factors to improve or replace biological functions. While it was once categorized as a sub-field of bio materials, having grown in scope and importance it can be considered as a field in its own right. While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells to produce tissues.
The frames around which something is built, like a bladder or tube would use a support structure. There is a move to a system like 3D printing too, which provides its own scaffolding sort of, as the structure is built up in layers.

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