Safety issues related to aluminum sheets include the risk of cuts and lacerations from sharp edges, potential for eye injuries if aluminum particles or dust comes into contact with the eyes, and the risk of fire or explosion if aluminum dust is present in the air and ignited. Additionally, improper handling can lead to back injuries or other musculoskeletal disorders due to the weight of the sheets. Inhalation of aluminum dust over a long period may also pose health risks, although it's less common. It's crucial to use proper protective equipment and follow safety guidelines when working with aluminum sheets.