i want to know because we have a new computer and we don't want to keep taking the case off
If that Card reader was designed to be mounted inside the computer case (into a floppy bay, for example), then typically it will be designed to be plugged onto the motherboard via one of the USB headers on the board. You will know when you read the packaging, what it requires to work. Some readers come with firewire connections as well, so just be mindful of that.