Will the kind of adhesive soluble in water (preferably powder), melting temperature of about 800 degrees, was neutral or weak alkaline, thank you!
Sodium alginate was crosslinked with glutaraldehyde under acidic conditions and poured into ethanol solution to prepare sodium dithiocortate containing diclofenac sodium (slightly soluble in water). The embedding rate is 30% to 71%, depending on the preparation conditions. When the ball is prepared, the temperature is increased or the exposure time of the crosslinked substance is prolonged, the embedding rate is reduced and the drug release time is prolonged
Alginate is slightly soluble in water and insoluble in most organic solvents. It is dissolved in alkaline solution, so that the solution is viscous. Sodium alginate alginate is hygroscopic and the amount of moisture contained in the equilibrium depends on the relative humidity. The dried sodium alginate is stored fairly stable in a well-sealed container at 25 ° C and below. Sodium alginate solution is stable at pH 5 to 9. The degree of polymerization (DP) and the molecular weight are directly related to the viscosity of the sodium alginate solution, and the decrease in viscosity during storage can be used to estimate the degree of sodium alginate de-polymerization. High degree of polymerization of sodium alginate stability is less than the degree of polymerization of sodium alginate. It is reported that sodium alginate can be catalyzed by proton hydrolysis, which depends on time, pH and temperature. The propylene glycol alginate solution is stable at room temperature at pH 3 to 4; when the pH is less than 2 or greater than 6, the viscosity will decrease even at room temperature. The sodium powder is wet with water and the hydration of the particles makes the surface sticky. The particles are then quickly bonded together to form clumps, and the agglomerates are slowly and completely hydrated and dissolved. Alginate is more difficult to dissolve in water if it contains other compounds that compete with alginate for hydration. Water in the sugar, starch or protein will reduce the rate of sodium alginate hydration, mixing time necessary to extend. A monovalent cation (such as NaCl) also has a similar effect at concentrations above 0.5%. The pH of sodium alginate in 1% distilled water was about 7.2....
Alginate is slightly soluble in water and insoluble in most organic solvents. It is dissolved in alkaline solution, so that the solution is viscous. Sodium alginate powder wet with water, the hydration of particles to make its surface with a sticky. The particles are then quickly bonded together to form clumps, and the agglomerates are slowly and completely hydrated and dissolved. Alginate is more difficult to dissolve in water if it contains other compounds that compete with alginate for hydration. Water in the sugar, starch or protein will reduce the rate of sodium alginate hydration, mixing time necessary to extend. A monovalent cation (such as NaCl) also has a similar effect at concentrations above 0.5%. Sodium alginate has a pH of about 7.2 in 1% distilled water.
